Arsenic Health Effects Research Program and Related Publications



Ferreccio C, Smith AH, Durán V, Barlaro T, Benítez H, Valdés R, Aguirre JJ, Moore LE, Acevedo J, Vásquez MI, Pérez L, Yuan Y, Liaw J, Cantor KP, Steinmaus C. Case-control study of arsenic in drinking water and kidney cancer in uniquely exposed northern Chile. Am J Epidemiol 2013 Jun 13 [epub ahead of print]. [PDF]

Kalman DA, Dills RL, Steinmaus C, Yunus M, Khan AF, Prodhan MM, Yuan Y, Smith AH. Occurrence of trivalent monomethyl arsenic and other urinary arsenic species in a highly exposed juvenile population in Bangladesh. J Expo Sci Environ Epidemiol 2013 Apr 3 [epub ahead of print].  [PDF]

Smith AH. Arsenic and diabetes. Environ Health Perspect 121(3):A70-1, 2013.  [PDF]

Steinmaus C, Miller MD, Cushing L, Blount BC, Smith AH. Combined effects of perchlorate, thiocyanate, and iodine on thyroid function in the National Health and Nutrition Examination Survey 2007-08. Environ Res 123:17-24, 2013.  [PDF]

Steinmaus C,  Ferreccio C, Romo JA, Yuan Y, Cortes S, Marshall G, Moore LE, Balmes JR, Liaw J, Golden T, Smith AH. Drinking water arsenic in northern Chile: high cancer risks 40 years after exposure.  Cancer Epidemiol Biomarkers 22(4):623-30, 2013. [PDF]

Smith AH, Marshall G, Liaw J, Yuan Y, Ferreccio C, Steinmaus C. Mortality in young adults following in utero and childhood exposure to arsenic in drinking water. Environ Health Perspect 120(11):1527-31, 2012. [PDF]

Smith AH, Steinmaus C. Arsenic in drinking water. BMJ 342:d2248, 2011. [PDF]

Smith AH, Steinmaus C. Arsenic in drinking water increases mortality from cardiovascular disease.  2011; doi: 10.1136/bmj.d2248. [PDF]

Basu A, Mitra S, Chung J, Mazumder DNG, Ghosh N, Kalman D, von Ehrenstein OS, Steinmaus C, Liaw J, Smith AH. Creatinine, Diet, Micronutrients, and Arsenic Methylation in West Bengal, India.  Environ Health Perspect. 119:1308-1313, 2011. [PDF]

Dauphine DC, Ferreccio C, Guntur S, Yuan Y, Hammond SK, Balmes J, Smith AH, Steinmaus C. Lung function in adults following in utero and childhood exposure to arsenic in drinking water: preliminary findings.  Int Arch Occup Environ Health 84:591-600, 2011. [PDF]

Steinmaus C, Smith AH, Smith MT. Regarding “meta-analysis and causal inference: a case study of benzene and non-Hodgkins lymphoma”: an incomplete analysis. Ann Epidemiol 2011 Jan; 21(1):67-9, 2011. [PDF]

Ren X, McHale CM, Skibola CF, Smith AH, Smith MT, Zhang L. An Emerging Role for Epigenetic Dysregulation in Arsenic Toxicity and Carcinogenesis.  Environ Health Perspect. 119:11-19, 2011. [PDF]

Steinmaus C, Miller M, Smith AH. Perchlorate in Drinking Water During Pregnancy and Neonatal Thyroid Hormone Levels in California. J Occup Environ Med. 52:1217-1224, 2010. [PDF]

Rahman A, Persson L, Nermell B, Arifeen S, Ekstrom E, Smith AH, Vahter M. Arsenic Exposure and Risk of Spontaneous Abortion, Stillbirth, and Infant Mortality. Epidemiology. 21:797-804, 2010. [PDF]

Smith AH,  Marshall G, Yuan Y, Liaw J, Ferreccio C, Steinmaus C. Evidence from Chile that arsenic in drinking water may increase mortality from pulmonary tuberculosis. Am J Epidemiol 173(4):414-20, 2011. [PDF]

Steinmaus C, Yuan Y, Kalman D, Rey O, Skibola C, Dauphine D, Basu A, Porter K, Hubbard A, Bates M, Smith MT, Smith AH. Individual differences in arsenic metabolism and lung cancer in a case-control study in Cordoba Argentina. Toxicol. Appl. Pharmacol. 247:138-145, 2010. [PDF]

Schwilk E, Zhang L, Smith MT, Smith AH, Steinmaus C. Formaldehyde and leukemia: An updated meta-analysis and evaluation of bias. Occup. Environ. Med. 52:878-886, 2010. [PDF]

Porter K, Basu A, Bates M, Kalman D, Rey O, Smith AH, Smith MT, Steinmaus C, Skibola C. Association of Genetic Variation in Cystathionine-β-synthase and Arsenic Metablolism. Environ Res 2010. [PDF]

Yuan Y, Marshall G, Ferreccio C, Steinmaus C, Liaw J, Bates M, Smith AH. Kidney cancer mortality: Fifty-year latency patterns related to arsenic exposure. Epidemiology. 21:103-108, 2010. [PDF]

Jo WJ, Loguinov A, Wintz H, Chang M, Smith AH, Kalman D, Zhang L, Smith MT, Vulpe CD. Comparative Functional Genomic Analysis Identifies Distinct and Overlapping Sets of Genes Required for Resistance to Monomethylarsonous Acid (MMAIII) and Arsenite (AsIII) in Yeast. Toxicol. Sci. 111(2), 424-436, 2009. [PDF]

Steinmaus C, Yuan Y, Liaw J, Smith AH.  Low-level population exposure to inorganic arsenic in the United States and Diabetes Mellitus: A Reanalysis. Epidemiology. 20:807-815, 2009. [PDF]

Smith AH, Ercumen A, Yuan Y, Steinmaus C. Increased Lung Cancer Risks are Similar Whether Arsenic is Ingested or Inhaled. J Expo Sci Environ Epidemiol  19, 344-346 2009. NIHMSID: NIHMS 108231. [PDF]

Smith AH, Steinmaus C. Health Effects of Arsenic and Chromium in Drinking Water: Recent Human Findings. Annu. Rev. Public Health  30:9.1-9.16, 2009. NIHMSID: NIHMS 108198. [PDF]

Smith AH. Hexavalent chromium, yellow water, and cancer: A convoluted saga. Epidemiology. 19(1):24-26, 2008. [PDF] Commentary on this article and our author response: Paustenbach DJ. On the chromium reanalysis. Epidemiology. 20(4):625-626. Author reply: 626-627, 2009. [PDF]

Rahman A, Vahter M, Smith AH, Nermell B, Yunus M, El Arifeen S, Persson L, Ekstrom E.  Arsenic Exposure During Pregnancy and Size at Birth: A Prospective Cohort Study in Bangladesh. Am J Empidemiol. 169:304-312, 2008. [PDF]

Liaw J, Marshall G, Yuan Y, Ferreccio C, Steinmaus C, Smith AH.
Increased Childhood Liver Cancer Mortality and Arsenic in Drinking Water in Northern Chile. Cancer Epidemiol Biomarkers Prev. 17(8):1982-87, 2008. NIHMSID: NIHMS 108448. [PDF]

Hegedus CM, Skibola CF, Warner M, Skibola DR, Alexander D, Lim S, Dangleben NL, Zhang L, Clark M, Pfeiffer RM, Steinmaus C, Smith AH, Smith MT, Moore LE. Decreased urinary beta-defensin-1 expression as a biomarker of response to arsenic. Toxicol Sci 106(1):74-82, 2008. [PDF]

Steinmaus C, Yuan Y, Liaw J, Smith AH.  On Arsenic, Diabetes, Creatinine, and Multiple Regression Modeling: A Response to the Commentaries on our Reanalysis. Epidemiology. 20(6):e1-e2. DOI: 10.1097/EDE.0b013e3181ba360b. [PDF]

Steinmaus C, Smith AH, Jones RM, Smith MT. Meta-analysis of benzene exposure and non-Hodgkin lymphoma: biases could mask an important association. Occup. Environ. Med. 65:371-378, 2008. [PDF]

Yuan Y, Marshall G, Ferreccio C, Steinmaus C, Selvin S, Liaw J, Bates MN, Smith AH. Acute myocardial infarction mortality in comparison with lung and bladder cancer mortality in arsenic-exposed Region II of Chile from 1950 to 2000.  Am J Epidemiol. 166:1381-1391, 2007. [PDF]

Marshall G, Ferreccio C, Yuan Y, Bates MN, Steinmaus C, Selvin S, Liaw J, Smith AH. Fifty-year study of lung and bladder cancer mortality in Chile related to arsenic in drinking water.  J Natl Cancer Inst 99:920-928, 2007. [PDF]

Smith MT, Jones RM, Smith AH. Benzene exposure and risk of non-Hodgkin lymphoma. Cancer Epidemiol Biomarkers Prev 16:385-91, 2007. [PDF]

Steinmaus C, Moore LE, Shipp M, Kalman D, Rey OA, Biggs ML, Hopenhayn C, Bates MN, Zheng S, Wiencke JK, Smith AH. Genetic polymorphisms in MTHFR 677 and 1298, GSTM1 and T1, and metabolism of arsenic. J Toxicol Environ Health A 70:159-70, 2007. [PDF]

von Ehrenstein OS, Poddar S, Yuan Y, Guha Mazumder DN, Eskenazi B, Basu A, Hira-Smith M, Ghosh N, Lahiri S, Haque R, Ghosh A, Kalman D, Das S, Smith AH.. Children’s intellectual function in relation to arsenic exposure. Epidemiology 18:44-51, 2007. [PDF]

Hira-Smith MM, Yuan Y, Savarimuthu X, Liaw J, Hira A, Green C, Hore T, Chakraborty P, von Ehrenstein OS, Smith AH. Arsenic concentrations and bacterial contamination in a pilot shallow dugwell program in West Bengal, India. J Environ Sci Health A 42: 89-95, 2007. [PDF]

George CM, Smith AH, Kalman DA, Steinmaus CM. Reverse osmosis filter use and high arsenic levels in private well water. Arch Environ Occup Health 61:171-175, 2006. [PDF]

von Ehrenstein OS, Guha Mazumder DN, Hira-Smith MM, Ghosh N, Yuan Y, Windham G, Ghosh A, Haque R, Lahiri S, Kalman D, Das S, Smith AH. Pregnancy Outcomes, Infancy Mortality, and Arsenic in Drinking Water in West Bengal, India. Am J Epidemol 163:662-669, 2006. [PDF]

Savarimuthu X, Hira-Smith MM, Yuan Y, von Ehrenstein OS,  Das S, Ghosh N, Guha Mazumder DN, Smith AH. Seasonal variation of arsenic concentration in tube wells in West Bengal, India. J Health Popul Nutr 24:277-281, 2006. [PDF]

Chung JS, Haque R, Guha Mazumder DN, Moore LE, Ghosh N, Samanta S, Mitra S, Hira-Smith MM, von Ehrenstein O, Basu A, Liaw J, Smith AH. Blood concentrations of methionine, selenium, beta-carotene, and other micronutrients in a case-control study of arsenic-induced skin lesions in West Bengal, India. Environ Research 101:230-237, 2006. [PDF]

von Ehrenstein OS, Jenny A, Basu A, Smith KR, Hira-Smith M, Smith AH. Capacity building in environmental health research in India and Nepal. Int J Occup Environ Health12:300-6, 2006. [PDF]

Steinmaus CM, George CM, Kalman DA, Smith AH. The evaluation of two new arsenic field test kits capable of detecting arsenic water concentrations close to 10 mg/l. Environ Sci Technology 40:3362-6, 2006. [PDF]

Smith AH, Marshall G, Yuan Y, Ferreccio C, Liaw J, von Ehrenstein OS, Steinmaus1, Bates MN, and Selvin S. Increased mortality from lung cancer and bronchiectasis in young adults following exposure to arsenic in utero and early childhood. Environ Health Perspect 114:1293-96, 2006. [PDF]

Steinmaus C, Bates MN, Yuan Y, Kalman D, Atallah R, Rey O, Biggs ML, Hopenhayn C, Moore L, Hoang B, Smith AH. Arsenic methylation and bladder cancer risk in case-control studies in Argentina and the United States. J Occup Environ Med. 48:478-88, 2006. [PDF]

Mazumder DNG, Steinmaus C, Bhattacharya P, von Ehrenstein O, Ghosh N, Gotway M, Sil A, Balmes JR, Haque R, Hira-Smith MM, Smith AH.   Bronchiectasis in persons with skin lesions resulting from arsenic in drinking water. Epidemiology. 2005 Nov; 16(6);760-5. [PDF] 

Steinmaus CM, Yuan Y, Smith AH. The temporal stability of arsenic concentrations in well water in western Nevada. Environ Res. 2005 Oct; 99(2):164-8.  [PDF] 

Steinmaus C, Carrigan K, Kalman D, Atallah R, Yuan Y, Smith AH. Dietary intake and arsenic methylation in a U.S. population. Environ Health Perspect. 2005 Sep; 113(9):1153-9.  [PDF] 

von Ehrenstein OS, Guha Mazumder DN ,Yuan Y, Samanta S, Balmes J, Sil A, Ghosh N, Hira-Smith M, Haque R, Purushothamam R, Lahiri S, Das S, Smith AH. Decrements in lung function related to arsenic in drinking water in West Bengal, India. Am J Epidemiol.. 2005 Sep;162(6):533-41. [PDF] 

Steinmaus C, Yuan Y, Kalman D, Atallah R, Smith AH. Intraindividual variability in arsenic methylation in a U.S. population. Cancer Epidemiol Biomarkers Prev. 2005 Apr;14(4):919-24.  [PDF] 

Mitra SR, Mazumder DN, Basu A, Block G, Haque R, Samanta S, Ghosh N, Smith MM, von Ehrenstein OS, Smith AH. Nutritional factors and susceptibility to arsenic-caused skin lesions in West Bengal, India. Environ Health Perspect. 2004 Jul;112(10):1104-9.  [PDF] 

Zhuo H, Smith AH and Steinmaus CM. Selenium and lung cancer: a quantitative analysis of heterogeneity in the current epidemiological literature. Cancer Epidemiol Biomarkers Prev 2004 13:771-8.  [PDF] 

Steinmaus CM, Lu M, Todd RL, Smith AH. Probability estimates for the unique childhood leukemia cluster in Fallon, Nevada, and risks near other U.S. military aviation facilities. Environ Health Perspect 2004 112:766-71. [PDF] 

Smith AH and Smith MM. Arsenic drinking water regulations in developing countries with extensive exposure. Toxicology 2004 May 20; 198(1-3):39-44.  [PDF] 

Moore LE, Wiencke JK, Bates MN, Zheng S, Rey OA, Smith AH. Investigation of genetic polymorphisms and smoking in a bladder cancer case-control study in Argentina. Cancer Lett 2004 Aug 10; 211(2): 199-207.  [PDF] 

Bates MN, Rey OA, Biggs ML, Hopenhayn C, Moore LE, Kalman D, Steinmaus C, Smith AH. Case-control study of bladder cancer and exposure to arsenic in Argentina. Am J Epidemiol 2004 Feb 15; 159(4): 381-9. [PDF] 

Bates MN, Buckland SJ, Garrett N, Ellis H, Needham LL, Patterson DG, Turner WE, Russel DG. Persistent organochlorines in the serum of the non-occupationally exposed New Zealand population. Chemosphere 2004 Mar; 54(10): 1431-43.  [PDF] 

Steinmaus C, Yuan Y, Bates MN, Smith AH. Case-control study of bladder cancer and drinking water arsenic in Western United States. Am J Epidemiol 2003 Dec 15; 158(12): 1193-1201.  [PDF] 

Smith MM, Hore T, Chakraborty P, Chakraborty DK, Savarimuthu X, Smith AH. A dugwell program to provide arsenic-safe water in West Bengal, India: preliminary results. J Environ Sci Health Part A Tox Hazard Subst Environ Eng. 2003 Jan;38(1):289-99.  [PDF] 

Moore LE, Smith AH, Eng C, Sandy D, Kalman D, Bhargava V, Chew K, Ferreccio C, Rey OA, Hopenhayn C, Biggs ML, Bates MN, Waldman FM. P53 Alterations in bladder tumors from arsenic and tobacco exposed patients. Carcinogenesis. 2003 Nov;24(11):1785-1791.  [PDF] 

Haque R, Mazumder DN, Samanta S, Ghosh N, Kalman D, Smith MM, Mitra S, Santra A, Lahiri S, Das S, De BK, Smith AH. Arsenic in drinking water and skin lesions: dose-response data from West Bengal, India. Epidemiology. 2003 Mar;14(2):174-82.  [PDF] 

Claudio L. Building self-reliance in environmental science: the ITREOH experience. Epidemiology. 2003 Jul;111(9):A460-32. [PDF] 

Smith AH, Lopipero PA, Bates MN, Steinmaus C. Public health. Arsenic epidemiology and drinking water standards. Science. 2002 Jun 21;296(5576):2145-6. [PDF] 

Moore LE, Lu M, Smith AH Childhood cancer incidence and arsenic exposure in drinking water in Nevada. Arch Environ Health. 2002 May-Jun;57(3):201-6.  [PDF] 

Moore LE, Smith AH, Eng C, Kalman D, DeVries S, Bhargava V, Chew K, Moore D 2nd, Ferreccio C, Rey OA, Waldman FM. Arsenic-related chromosomal alterations in bladder cancer. J Natl Cancer Inst. 2002 Nov;94(22):1688-96.  [PDF] 

Chung JS, Kalman DA, Moore LE, Kosnett MJ, Arroyo AP, Beeris M, Mazumder DN, Hernandez AL, Smith AH. Family correlations of arsenic methylation patterns in children and parents exposed to high concentrations of arsenic in drinking water. Environ Health Perspect. 2002 Jul;110(7):729-33.  [PDF] 

Bates MN, Selevan SG, Ellerbee SM, Gartner LM Reporting needs for studies of environmental chemicals in human milk. J Toxicol Environ Health A. 2002 Nov 22;65(22):1867-79.  [PDF] 

Smith AH, Lopipero P. Invited commentary: how do the Seveso findings affect conclusions concerning TCDD as a human carcinogen? Am J Epidemiol. 2001 Jun 1;153(11):1045-7,1048-9. [PDF] 

Moore L, Wiencke J, Eng C, Zheng S, Smith AH. Evaluation of buccal cell collection protocols for genetic susceptibility studies. Biomarkers, 6: 448-54, 2001. [PDF] 

Steinmaus, C, Nuñez S, Smith AH. Diet and bladder cancer: a meta-analysis of six dietary variables. Am J Epidemiol. 2000 Apr 1;151(7):693-702. [PDF] 

Steinmaus C, Moore LE, Hopenhayn-Rich C, Biggs ML, Smith AH. Arsenic in drinking water and bladder cancer. Cancer Invest. 2000 Feb;18(2):174-82.  [PDF] 

Smith AH, Arroyo AP, Guha Mazumder DN, Kosnett MJ, Hernandez AL, Beeris M, Smith T, Moore LE. Arsenic-induced skin lesions among Atacameño people in northern Chile despite good nutrition and centuries of exposure. Environ Health Perspect. 2000 Jul;108(7):617-20.  [PDF] 

Smith AH, Lingas EO, Rahman M. Contamination of drinking-water by arsenic in Bangladesh: a public health emergency. Bull World Health Organ. 2000 Sept;78(9):1093-103.  [PDF] 

Smith AH, Steinmaus CM. Arsenic in urine and drinking water [letter] Environ Health Perspect. 2000 Nov;108(11):A494-5.  [PDF] 

Moore LE, Godfrey T, Eng C, Smith AH, Ho R, Waldman FM. Validation of flourescent SSCP analysis for sensitive detection of p53 mutations. Biotechniques. 2000 28:986-92.  [PDF] 

Guha Mazumder DN, Haque R, Ghosh N, De BK, Santra A, Chakraborti D, Smith AH. Arsenic in drinking water and the prevalence of respiratory effects in West Bengal, India. Int J Epidemiol. 2000 Dec;29(6):1047-52.  [PDF] 

Ferreccio C, González C, Milosavjlevic V, Marshall G, Sancha AM, Smith AH. Lung cancer and arsenic concentrations in drinking water in Chile. Epidemiology. 2000 Nov;11(6):673-9.  [PDF] 

Smith AH, Biggs ML, Moore LE, Haque R, Steinmaus C, Chung J, Hernandez AL, Lopipero P. Cancer risks from arsenic in drinking water: implications for drinking water standards. In: W Chappell, CO Abernathy and RL Calderon (eds.): Arsenic esposure and health effects: proceedings of the Third International Conference on Arsenic Exposure and Health Effects, July 12-15, 1998, San Diego, California. Oxford: Elsevier Science, Ltd., pp.191-99, 1999.  [PDF] 

Smith AH. Amphibole fibers, chrysotile fibers, and pleural mesothelioma. Am J Ind Med. 1998 33:96.  [PDF] 

Smith AH, Goycolea M, Haque R, Biggs ML. Marked increase in bladder and lung cancer mortality in a region of Northern Chile due to arsenic in drinking water. Am J Epidemiol. 1998 Apr 1;147(7):660-9.  [PDF] 

NIEHS Center for Environmental Health Sciences. Newsletter: International environmental health research. NIEHS Newsletter. 1998 Spring:1-3.  [PDF] 

Hopenhayn-Rich C, Biggs ML, Smith AH. Lung and kidney cancer mortality associated with arsenic in drinking water in Cordoba, Argentina. Int J Epidemiol. 1998 Aug;27(4):561-9.  [PDF] 

Guha Mazumder DN, Haque R, Ghosh N, De BK, Santra A, Chakraborti D Smith AH. Arsenic levels in drinking water and the prevalence of skin lesions in West Bengal, India. Int J Epidemiol. 1998 Oct;27(5):871-7. [PDF] 

Biggs ML, Haque R, Moore L, Smith AH. Arsenic-laced water in Chile [letter; comment] Science. 1998 Aug 7;281(5378):785. [HTML] 

Bhatia R, Lopipero P, Smith AH. Diesel exhaust exposure and lung cancer. Epidemiology. 1998 Jan;9(1):84-91. [summary] 

Smith AH. Technical Report. Assignment Report, WHO Project BAN CWS 001 June 1998. [PDF] 

Smith AH. Technical Report And Review Of Action Plan For Arsenic In Drinking Water In Bangladesh Focusing On Health Assignment Report, WHO Project BAN CWS 001/D February 1998. [PDF] 

Smith AH. Report and Action Plan for Arsenic in Drinking Water Focusing on Health, Bangladesh. Assignment Report, WHO Project BAN CWS 001 March 1997. [PDF] 

Wright C, Lopipero P, Smith AH. Meta-analysis and Risk Assessment. In: Topics in Environmental Epidemiology Eds. Steenland K and Savitz DA: Oxford University Press, 1996. [PDF] 

Moore, LE, Smith AH, Hopenhayn-Rich C, Biggs ML, Kalman DA, Smith MT. Decrease in bladder cell micronucleus prevalence after intervention to lower the concentration of arsenic in drinking water. Cancer Epidemiol Biomarkers & Prev. 1997 Dec;6(12):1051-6. [PDF] 

Moore LE, Smith AH, Hopenhayn-Rich C, Biggs ML, Kalman DA, Smith MT. Micronuclei in exfoliated bladder cells among individuals chronically exposed to arsenic in drinking water. Cancer Epidemiol Biomarkers & Prev. 1997 Jan;6(1):31-6. [PDF] 

Biggs ML, Kalman DA, Moore LE, Hopenhayn-Rich C, Smith MT, Smith AH. Relationship of urinary arsenic to intake estimates and a biomarker of effect, bladder cell micronuclei. Mutat Res. 1997 Jun;386(3):185-95. [PDF] 

Aposhian HV, Arroyo A, Cebrian M, Del Razo LM, Hurlbut KM, Dart RC, Gonzalez-Ramirez D, Kreppel H, Speiske H, Smith AH, Gonsebatt ME, Ostrosky-Wegman P, Aposhian MM. DMPS-Arsenic Challenge Test: I-Increased Urinary Excretion of Monomethylarsonic Acid in Humans Given Dimercaptopropane Sulfonate. J Pharmacol Exp Ther. 1997 Jul;282(1):192-200.  [PDF] 

Smith AH, Sciortino S, Goeden H, Wright CC. Consideration of background exposures in the management of hazardous waste sites: a new approach to risk assessment. Risk Anal. 1996 Oct;16(5): 619-25. [PDF] 

Smith AH, Wright CC. Chrysotile asbestos is the main cause of pleural mesothelioma. Am J Ind Med. 1996 Sep;30(3): 252-66. [PDF] 

Moore L, Warner ML, Smith AH, Kalman D, Smith MT. Use of the fluorescent micronucleus assay to detect the genotoxic effects of radiation and arsenic in human exfoliated epithelial cells. Environ Mol Mutagen. 1996;27(3):176-84. [PDF] 

Mendel MJ, Fisk WJ, Deddens JA, Seavey WG, Smith AH, Smith DF, Hodgson AT, Daisey JM, Goldman LR. Elevated symptom prevalence associated with ventilation type in office buildings. Epidemiology. 1996 Nov; 7:(6) 583-9. [PDF] 

Hopenhayn-Rich C, Biggs ML, Smith AH, Kalman D, Moore LE. Methlyation study in a population environmentally exposed to high arsenic water. Environ Health Perspect. 1996 Jun;104(6):620-8.  [PDF] 

Hopenhayn-Rich C, Biggs ML, Kalman D, Moore LE, Smith AH. Arsenic methylation patterns before and after changing from higher to lower concentrations of arsenic in drinking water. Environ Health Perspect. 1996 Nov;104(11):1200-7.  [PDF] 

Hopenhayn-Rich C, Biggs ML, Fuchs A, Bergoglio R, Tello E, Nicolli H, Smith AH. Bladder cancer mortality associated with arsenic in drinking water in Argentina. Epidemiology. 1996 Mar;7(2):117-24. [PDF] 

Holly EA, Aston DA, Ahn DK, Smith AH. Intraocular melanoma linked to occupations and chemical exposures. Epidemiology. 1996 Jan;7(1):55-61. [summary] 

Brown KG, Beck BD. Arsenic and bladder cancer mortality. Epidemiology. 1996 Sep;7(5):557-8. [PDF] 

Smith AH. Epidemiology: bias bias everywhere? and not a drop of science? In: Graham JD (ed) The Role of Epidemiology in Regulatory Risk Assessment. Elsevier Science: Boston 1995 39-43. 


Smith AH, Wright C. Environmental risk assessment using epidemiologic data. In: Host Factors in Environmental Epidemiology, Cracow, Central and Eastern European Chapter, ISEE/ISEA, 1995, 9-25. 


Smith AH, Hopenhayn-Rich C, Biggs ML, Kalman D. Re: Arsenic risk assessment. [letter; comment]. Environ Health Perspect. 1995 Jan;103(1):13-7.  [PDF] 

Smith AH, Lopipero PA, Barroga VR. Meta-analysis of studies of lung cancer among silicotics. Epidemiology. 1995 Nov;6(6):617-24. [summary] 

Moore L, Smith AH, Hopenhayn-Rich C, Biggs ML, Warner ML, Kalman D, Smith MT. Increased bladder cell micronuclei found in two populations environmentally exposed to arsenic in drinking water. Clin Chem. Dec 1995 41(12): 1915-7. [summary] 

Bates MN, Smith AH, Cantor KP. Case-control study of bladder cancer and arsenic in drinking water. Am J Epidemiol. 1995 Mar 15;141(6):523-30. [summary] 

Warner M, Moore L, Smith MT, Kalman D, Fanning E, Smith AH. Increased micronuclei in exfoliated bladder cells of persons who chronically ingest arsenic contaminated water in Nevada. Cancer Epidemiol Biomarkers & Prev. 1994 Oct-Nov;3(7):583-90. [summary] 

Smith AH, Hopenhayn-Rich C, Biggs ML, Moore L, Dale J, Warner M, Bates M, Engel R. Epidemiological study designs to address potential high bladder cancer risks from arsenic in drinking water. In: Chappell WR, Abernathy CO, Cothern CR (eds): Arsenic: Exposure and Health Northwood: Science and Technology Letters: 109-17, 1994. [summary] 

Smith AH, Duggan HM, Wright C. Assessment of cancer clusters using limited cohort data with spreadsheets: application to a leukemia cluster among rubber workers. Am J Ind Med. 1994;25(6):813-23. [summary] 

Engel RR, Hopenhayn-Rich C, Receveur O, Smith AH. Vascular effects of chronic arsenic exposure: a review. Epidemiol Rev. 1994;16(2):184-209. [summary] 

Engel RR, Smith AH. Arsenic in drinking water and mortality from vascular disease: an ecologic analysis in 30 U.S. counties. Arch Environ Health. 1994 Sep-Oct;49(5):418-27. [summary] 

Waller DK, Lustig LS, Smith AH, Hook EB. Alpha-fetoprotein: a biomarker for pregnancy outcome. Epidemiology. 1993 Sep;4(5):471-6. [summary] 

Smith AH, Hopenhayn-Rich C, Warner M, Biggs ML, Moore L, Smith MT. Rationale for selecting exfoliated bladder cells micronuclei as potential biomarkers for arsenic genotoxicity. J Toxicol Environ Health. 1993 Oct-Nov;40(2-3):223-34. [summary

Hertz-Picciotto I, Smith AH. Observations on the dose-response curve for arsenic exposure and lung cancer. Scand J Work Environ Health. 1993 Aug;19(4):217-26. [summary] 

Hopenhayn-Rich C, Smith AH, Goeden H. Human studies do not support the methylation threshold hypothesis for the toxicity of inorganic arsenic. Environ Res. 1993 Feb;60(2):161-77. [summary] 

Engel RR, Receveru O. Re: "Arsenic ingestion and internal cancers: a review". Am J Epidemiol. 1993 Nov 15;138(10):896-7. [PDF] 

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